Anthrax

Anthrax is an infectious disease that can affect the skin, the lungs, as well as the mouth, throat and gastrointestinal tract. The infection sometimes can spread to other parts of the body, especially if treatment is not started early. For example, anthrax could, very rarely, lead to inflammation of the meninges (meningitis).

Anthrax is caused by a bacterium called Bacillus anthracis. The bacteria occur in living tissue of infected animals. The bacteria can form spores under certain conditions when, for example, body fluids infected with the bacteria are exposed to the air. The bacteria cannot live for long outside an animal. On the other hand, the spores can survive in soil and some other materials for decades.

To multiply, Bacillus anthracis produces small spores. When these spores enter a cut or abrasion on the skin they start a skin infection usually called cutaneous anthrax. If the spores are inhaled, they are small enough that they enter the lungs and cause inhalation anthrax. Eating contaminated, undercooked meat can cause oropharyngeal (mouth and throat) and gastrointestinal anthrax.

No. Spreading anthrax from person to person is extremely unlikely to occur. It also requires a relatively large dose to infect a person – one would have to inhale 8,000 to 50,000 spores. Smallpox takes only 10 to 100 organisms to cause the disease.

Symptoms of the disease vary depending on how the disease was contracted. Symptoms usually occur within 7 days of exposure, but usually between 2 to 5 days. The skin infection begins with itchy bumps that resemble insect bites. Skin bumps develop into painless black blisters.

If the Bacillus anthracis spores are inhaled, the initial signs of disease are usually flu-like symptoms including fever, sore throat, feeling unwell, body aches, fatigue, cough and chest discomfort. The symptoms may progress to severe breathing problems.

In the case of intestinal anthrax symptoms usually begin a few days after ingestion of the contaminated meat. The symptoms include fever, chills, swelling of neck or neck glands, abdominal pain, fever, nausea, loss of appetite, vomiting and diarrhea.

Confirmation of a anthrax diagnosis requires laboratory examinations which identify Bacillus anthracis in the blood, skin lesions or respiratory secretions.

Laboratory blood tests can also detect whether the amount of certain specific protein (i.e. antibodies) has increased in the blood. An increase indicates infection by Bacillus anthracis. Antibodies are produced by special cells of the body's infection defense system to reduce or neutralize the effect of invading microorganisms. Tests may also be done using skin lesion swabs, spinal fluid or respiratory secretions.

Anthrax can be controlled with antibiotics. To be effective, treatment should start early after exposure. If left untreated or if treatment starts too late, anthrax can be fatal.

Human anthrax is unusual in North American. The centre for Disease Control in British Columbia reports that a case in BC was seen in 2001, and 2 people were infected in 2006 in Saskatchewan (during an outbreak among animals (mainly cattle)). All these poeple developed skin infections and recovered. Human cases of digestive and lung anthrax have never been reported in Canada. Anthrax can be an occupational hazard for workers who process hides, hair, bone and bone products and wool. Animal breeders, slaughterhouse workers, trappers and hunters, fur industry workers, tanning and leather industry workers, veterinarians, or wildlife, agricultural, and laboratory workers who handle infected animals or animal products can also be at risk for the infection.

Workplaces which process animal products should have adequate ventilation systems including local exhaust system to reduce dust levels. Clean the workspace with a high-efficiency particulate (HEPA) air vacuum. Workers who handle raw animal materials should be informed about modes of transmission. Avoid shaking or beating hides, dry sweeping or using compressed air (for cleaning). Workers should follow good personal hygiene practices including care of skin abrasions. Workers should use adequate protective clothing (such as a properly fitted face mask or respirator (N-95), eye protection and protective gloves) and facilities for washing and changing clothes after work.

Health Canada recommends that laboratory workers who work with anthrax should follow biosafety level 3 practices in appropriately designed and maintained facilities.